Don's world, wicked, made to suffer in it (7)
I believe the answer is:
academe
'don's world' is the definition.
'academe' can be an answer for 'world' (academe is a kind of world). I'm not certain of the 'don's' bit.
'wicked made to suffer in it' is the wordplay.
'wicked' becomes 'ace' (ace can informally mean very good).
'to suffer' indicates an anagram (I've seen 'suffers' mean this).
'in it' means one lot of letters goes inside another.
'made' is an anagram of 'adem'.
'ace' going around 'adem' is 'ACADEME'.
Can you help me to learn more?
(Other definitions for academe that I've seen before include "Educational environment" , "The world of education" , "college" , "The world of learning" , "Scholarly life" .)