Dote best, madly infatuated (8)
I believe the answer is:
besotted
'infatuated' is the definition.
(I've seen this before)
'dote best madly' is the wordplay.
'madly' indicates anagramming the letters.
'dote'+'best'='dotebest'
'dotebest' is an anagram of 'BESOTTED'.
(Other definitions for besotted that I've seen before include "Infatuated - so betted accordingly" , "Bested to become infatuated" , "Strongly infatuated" , "Showing foolish fondness" , "Doting" .)