Drug addicts surrounding hotel guides (6)
I believe the answer is:
ushers
'guides' is the definition.
(ushering is a kind of guiding)
'drug addicts surrounding hotel' is the wordplay.
'drug addicts' becomes 'users' (I've seen this before).
'surrounding' is an insertion indicator.
'hotel' becomes 'h' (phonetic alphabet: alpha, bravo, charlie etc.).
'users' placed around 'h' is 'USHERS'.
(Other definitions for ushers that I've seen before include "Theatre attendants" , "Officials stationed at the entrances of courtrooms" , "Do they lead" , "They show attendees to seats" , "They show people to their seats in theatres" .)