Drug I take during a trip (7)
I believe the answer is:
aspirin
'a trip' is the definition.
Although both the answer and definition are singular nouns, I cannot see how one could define the other.
'drug i take during' is the wordplay.
'drug' becomes 'asp' (I can't explain this - if you can you should give a lot more credence to this answer).
'take' becomes 'r' (abbreviation for 'recipe', Latin for 'take').
'during' becomes 'in' (e.g. during February means in February).
'asp'+'i'+'r'+'in'='ASPIRIN'
Can you help me to learn more?
(Other definitions for aspirin that I've seen before include "Mild pain-killing drug" , "answer to pain?" , "Anodyne" , "Common pain tablet" , "Headache pill" .)