Drunk cuddles horse in photograph (4)
I believe the answer is:
shot
'photograph' is the definition.
(I know that shot is a type of photograph)
'drunk cuddles horse' is the wordplay.
'drunk' becomes 'sot' (both can mean someone who drinks too much).
'cuddles' means one lot of letters goes inside another.
'horse' becomes 'h' (synonyms).
'sot' placed around 'h' is 'SHOT'.
'in' acts as a link.
(Other definitions for shot that I've seen before include "Fired; (be) rid (of)" , "Fired a gun" , "Photo; try" , "Short drink; attempt" , "glass of spirits" .)