Egomaniac should be upset and sorry (4,5)
I believe the answer is:
come again
'sorry' is the definition.
(both are used to ask someone to repeat something)
'egomaniac should be upset' is the wordplay.
'should be upset' indicates anagramming the letters (the letter order must be upset).
'egomaniac' with letters rearranged gives 'COME AGAIN?'.
'and' acts as a link.
(Other definitions for come again that I've seen before include "return invitation" , "Recall" , "Please clarify" , "I don't understand that" , "Turn out once more" .)