Either end of shinbone hurting (4)
I believe the answer is:
sore
'hurting' is the definition.
(synonyms)
'either end of shinbone' is the wordplay.
'either' becomes 'sor' (I can't justify this - if you can you should give a lot more credence to this answer).
'end of' suggests the final letters.
The last letter of 'shinbone' is 'e'.
'sor'+'e'='SORE'
Can you help me to learn more?
(Other definitions for sore that I've seen before include "Hard" , "Painful spot" , "very much" , "Wound; painful" , "Spot of aggravation" .)