Eliminated with one dope administered just regularly (5,3)
I believe the answer is:
wiped out
'eliminated' is the definition.
('wipe out' can be a synonym of 'eliminate')
'with one dope administered just regularly' is the wordplay.
I cannot quite see how this works, but
'with' could be 'w' (abbreviation) and 'w' is present in the answer.
'one' could be 'i' (Roman numeral) and 'i' is found in the answer.
an anagram of 'dope' is 'pedo' which is present in the answer.
The remaining letters 'ut' is a valid word which might be clued in a way I don't understand.
This explanation may well be incorrect...
Can you help me to learn more?
(Other definitions for wiped out that I've seen before include "Capsized while surfing" , "financially ruined" , "Destroyed completely" , "Killed to the last man" , "Ruined; killed" .)