Empty bistro and stuck-up old wine shop (6)
I believe the answer is:
bodega
'wine shop' is the definition.
(I've seen this before)
'empty bistro and stuck-up old' is the wordplay.
'empty' suggests removing the centre.
'and' says to put letters next to each other.
'stuck up' says the letters should be written in reverse.
'old' becomes 'aged' (similar in meaning).
'bistro' with its centre taken out is 'bo'.
'aged' reversed gives 'dega'.
'bo'+'dega'='BODEGA'
(Other definitions for bodega that I've seen before include "Liquor store" , "Spanish wine-shop" , "concern for alcohol" , "winestore" , "Wine supplier" .)