Entwined (5)
I believe the answer is:
laced
'entwined' is the definition.
('lace' can be a synonym of 'entwine')
This is the entire clue.
(Other definitions for laced that I've seen before include "Added alcohol to (drink)" , "Spiked drink - thrashed" , "Oxford will always be" , "Like some shoes" , "with extra spirit" .)