Face complaint about major road block (6)
I believe the answer is:
stymie
'block' is the definition.
(I know that block can be written as stymie)
'face complaint about major road' is the wordplay.
'face complaint' becomes 'stye' (I can't explain this - if you can you should believe this answer much more).
'about' means one lot of letters goes inside another.
'major road' becomes 'MI' (resembles Ms, English motorway).
'stye' going around 'mi' is 'STYMIE'.
Can you help me to learn more?
(Other definitions for stymie that I've seen before include "Thwart - block - my site (anag)" , "Block or thwart, perhaps on putting green" , "Obstruct as on putting green" , "Thwart (as once was possible on the green)" , "Tricky situation" .)