Farm building, for me, lacking new block (6)
I believe the answer is:
stymie
'block' is the definition.
(synonyms)
'farm building for me lacking new' is the wordplay.
'farm building' becomes 'sty'.
'for' means one lot of letters go next to another.
'me' becomes 'mi' (both are spellings of the musical note).
'lacking new' becomes 'e' (I am not sure about this - if you are sure you should believe this answer much more).
'sty'+'mi'+'e'='STYMIE'
Can you help me to learn more?
(Other definitions for stymie that I've seen before include "Thwart -- my ties (anag)" , "Block or obstruct as in golf (6)" , "Block; hinder" , "Block or thwart an activity" , "'Hinder, obstruct (6)'" .)