Fashion designer Jacobs (4)
I believe the answer is:
marc
'fashion designer jacobs' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for marc that I've seen before include "Strong liquor" , "Refuse from grapes after pressing - kind of brandy" , "Spirit" , "Brandy made from wine press residue" , "A brandy; --- Chagall, artist" .)