Female guest left off roll in academy, first of all (6)
I believe the answer is:
gloria
'female' is the definition.
(woman's name)
'guest left off roll in academy first of all' is the wordplay.
'first of all' says to take the initial letters.
The initial letters of 'guest left off roll in academy' is 'GLORIA'.
(Other definitions for gloria that I've seen before include "Girly part of the Mass?" , "U2, Van Morrison and Vivaldi have all sung about her" , "song used by worshippers" , "-- Gaynor, disco diva" , "Portion of Mass" .)