Make mistake with simple task (6)
I believe the answer is:
errand
'simple task' is the definition.
'make mistake with' is the wordplay.
'make mistake' becomes 'err' (I've seen this before).
'with' becomes 'and'.
'err'+'and'='ERRAND'
(Other definitions for errand that I've seen before include "Short journey to carry message for Renard" , "Task, message" , "Short journey done for others" , "Charge - mission" , "Mission (often run)" .)