Female without experience strangely genuine (7)
I believe the answer is:
ingenue
'female without experience' is the definition.
'strangely genuine' is the wordplay.
'strangely' indicates an anagram.
'genuine' anagrammed gives 'INGENUE'.
(Other definitions for ingenue that I've seen before include "Starlet" , "She's artless" , "Naive young actress" , "Inexperienced young woman" , "Naive female" .)