Find Leo upset about a spiteful woman (6)
I believe the answer is:
locate
'find' is the definition.
(locating is a kind of finding)
'leo upset about a spiteful woman' is the wordplay.
'upset' is an anagram indicator.
'about' means one lot of letters goes inside another.
'a spiteful woman' becomes 'cat'.
'leo' anagrammed gives 'loe'.
'loe' going around 'cat' is 'LOCATE'.
(Other definitions for locate that I've seen before include "Find out where something is" , "Find or situate" , "Lay one's hands on (something)" , "Find; lay hands on" , "Discover place where thing is" .)