Flight she had led topless and slightly drunk (5-6)
I believe the answer is:
light-headed
'slightly drunk' is the definition.
(light-headed can mean a bit drunk)
'flight she had led' is the wordplay.
'flight she' becomes 'light' (I am not sure about this - if you are sure you should believe this answer much more).
'had' says to put letters next to each other.
'led' becomes 'headed' (heading is a kind of leading).
'light'+'headed'='LIGHT-HEADED'
'topless and' acts as a link.
This may not be correct. Some or all of it may belong to another bit of the clue.
(Other definitions for light-headed that I've seen before include "Dizzy, slightly faint" , "without serious thought" .)