Fundamental shifting in cargo (7)
I believe the answer is:
organic
'fundamental' is the definition.
(I've seen this before)
'shifting in cargo' is the wordplay.
'shifting' indicates anagramming the letters.
'in'+'cargo'='incargo'
'incargo' is an anagram of 'ORGANIC'.
(Other definitions for organic that I've seen before include "No cigar (anag.)" , "Free of pesticides" , "Biological" , "Formed from living things - no cigar for this one" , "Derived from natural sources" .)