Game is designed in pictures (6)
I believe the answer is:
images
'pictures' is the definition.
(I know this)
'game is designed' is the wordplay.
'designed' indicates anagramming the letters (designed with the letters).
'game'+'is'='gameis'
'gameis' with letters rearranged gives 'IMAGES'.
'in' is the link.
(Other definitions for images that I've seen before include "Pictures or photos" , "Likenesses, representations" , "Semblances" , "works by Debussy" , "Photos or likenesses" .)