Gems that may appear strange in a new setting (7)
I believe the answer is:
garnets
'gems' is the definition.
(garnet is a kind of gem)
'may appear strange in a new setting' is the wordplay.
'strange' anagrams to 'GARNETS'.
However, I am unsure how this is indicated.
'that' is the link.
Can you help me to learn more?
(Other definitions for garnets that I've seen before include "Strange turn of the gemstones" , "Stones" .)