Girl, a female always getting a nasty illness (5,5)
I believe the answer is:
lassa fever
'a nasty illness' is the definition.
The definition suggests a singular noun which matches the answer.
'girl a female always' is the wordplay.
'girl' becomes 'lass' (lass is a kind of girl).
'female' becomes 'f' (common abbreviation).
'always' becomes 'ever' (synonyms).
'lass'+'a'+'f'+'ever'='LASSA FEVER'
'getting' is the link.
Can you help me to learn more?
(Other definitions for lassa fever that I've seen before include "Acute viral disease" , "Tropical viral disease that could kill" , "ailment" .)