Nearing the end of the holiday, everything else having gone wrong? (2,3,4,6)
I believe the answer is:
in the last resort
'the holiday everything else having gone wrong?' is the definition.
I don't know anything about this answer so I can't tell whether it can be defined by this definition.
'nearing the end of' is the wordplay.
I cannot really see how this works, but
'the' could be 't' (the is pronounced as a 't' sound in some dialects) and 't' is found in the answer.
'end' could be 'last' (I've seen this before) and 'last' is located in the answer.
'of' could be 'o' and 'o' is located in the answer.
This may be the basis of clue (or it may be nonsense).
Can you help me to learn more?
(Other definitions for in the last resort that I've seen before include "when all else has failed" , "finishing off a tour?" , "having no other hope of help?" , "Where one spent the previous holiday" , "how anagram was finally resolved?" .)