Give up pro game (5)
I believe the answer is:
forgo
'give up' is the definition.
(I know that give up can be written as forgo)
'pro game' is the wordplay.
'pro' becomes 'for' (I've seen this before).
'game' becomes 'go' (go is a board game).
'for'+'go'='FORGO'
(Other definitions for forgo that I've seen before include "Go without (something)" , "Do without (something desirable)" , "Relinquish, give up" , "Abjure" , "pass up" .)