Give up work and go to bed (6)
I believe the answer is:
retire
I believe this clue is a double definition.
'give up work' is the first definition.
(I've seen this before)
'go to bed' is the second definition.
(synonyms)
'and' acts as a link.
(Other definitions for retire that I've seen before include "Go to bed or quit work for good" , "Give up work for good" , "retreat" , "Finish employment" , "Give up the job and go to bed" .)