Give us directions for Customs? (4)
I believe the answer is:
uses
'customs?' is the definition.
(use is a kind of custom)
'give us directions' is the wordplay.
'give' is a charade indicator (letters next to each other).
'directions' becomes 'es' (east and south - two directions).
'us' next to 'es' is 'USES'.
'for' is the link.
(Other definitions for uses that I've seen before include "deployments" , "Sues (anag.)" , "What an employer does" , "Takes (drugs)" , "Exercises" .)