Gives up storing item in bureaus after losing a thousand (8)
I believe the answer is:
despairs
'gives up' is the definition.
(I've seen this in another clue)
'storing item in bureaus after losing a thousand' is the wordplay.
I cannot quite understand how this works, but
'item' could be 'pair' (both can mean a romantic couple) and 'pair' is found in the answer.
This may be the basis of the clue (or it may be nonsense).
Can you help me to learn more?
(Other definitions for despairs that I've seen before include "Loses all hope" , "Abandons hope" .)