Gone up to reset siren (5)
I believe the answer is:
risen
'gone up' is the definition.
('rise' can be a synonym of 'go up')
'reset siren' is the wordplay.
'reset' is an anagram indicator.
'siren' with letters rearranged gives 'RISEN'.
'to' acts as a link.
(Other definitions for risen that I've seen before include "Above the horizon" , "Ascended - revolted" , "Ascended - restored from death" , "Increased" , "Proved" .)