Gone up to reset siren (5)
I believe the answer is:
risen
'gone up' is the definition.
('rise' can be a synonym of 'go up')
'reset siren' is the wordplay.
'reset' indicates an anagram.
'siren' anagrammed gives 'RISEN'.
'to' is the link.
(Other definitions for risen that I've seen before include "Above the horizon" , "Ascended - revolted" , "Ascended - restored from death" , "Increased" , "Proved" .)