Guidance in case of acknowledged wrongdoing (6)
I believe the answer is:
advice
'guidance' is the definition.
(I've seen this before)
'case of acknowledged wrongdoing' is the wordplay.
'case of' means to remove the middle letters (outsides of).
'acknowledged' becomes 'avowed' (similar in meaning).
'wrongdoing' becomes 'vice' (vice is a kind of wrongdoing).
'avowed' with its middle removed is 'ad'.
'ad'+'vice'='ADVICE'
'in' is the link.
(Other definitions for advice that I've seen before include "Admonition" , "Supposed words of wisdom" , "Intelligence" , "Warning - guidance" , "Recommendation for a course of action" .)