Hamper queen following deer? (6)
I believe the answer is:
hinder
'hamper' is the definition.
(I know that hamper can be written as hinder)
'queen following deer?' is the wordplay.
'queen' becomes 'ER' (abbreviation for Elizabeth Regina).
'following' says to put letters next to each other.
'deer?' becomes 'hind' (hind is a kind of deer).
'er' put after 'hind' is 'HINDER'.
(Other definitions for hinder that I've seen before include "Obstruct or hold back" , "Handicap, impede" , "Delay progress, obstruct" , "Obstruct, create obstacle" , "Obstruct, impede" .)