Hindu Queen led India (4)
I believe the answer is:
rani
'hindu queen' is the definition.
(historical term for a Hindu queen)
'led india' is the wordplay.
'led' becomes 'ran' (to lead is to run or be in charge of).
'india' becomes 'i' (phonetic alphabet: alpha, bravo, charlie etc.).
'ran'+'i'='RANI'
(Other definitions for rani that I've seen before include "Rajah's wife from Iran" , "Raja's queen" , "Royal Indian female" , "Wife of a rajah" , "Indian princess" .)