Home with no money is guiltless (8)
I believe the answer is:
innocent
'is guiltless' is the definition.
(synonyms)
'home with no money' is the wordplay.
'home' becomes 'in' ('he's home' can mean 'he's in').
'with' is a charade indicator (letters next to each other).
'money' becomes 'cent' (eg denomination of dollars).
'in'+'no'+'cent'='INNOCENT'
(Other definitions for innocent that I've seen before include "otherworldly?" , "Naive person" , "Without blame or without guile" , "Pope" , "Name of 13 popes and one anti-pope" .)