I agree about large dog's cry of pain (4)
I believe the answer is:
yelp
'cry of pain' is the definition.
(I've seen this in another clue)
'i agree about large dog's' is the wordplay.
I cannot quite see how this works, but
'large' could be 'l' (eg in clothes sizes) and 'l' is found in the answer.
The remaining letters 'yep' is a valid word which might be clued in a way I don't see.
This may be the basis of the clue (or it may be nonsense).
Can you help me to learn more?
(Other definitions for yelp that I've seen before include "Short sharp cry or bark" , "Bark like a puppy" , "Cry of pain" , "Short sharp cry (of such as a dog)" , "Sharp shrill cry or bark" .)