I replace first article in bag which is completely tasteless (4)

I believe the answer is:

sick

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'i replace first article in bag which is completely tasteless' is the definition.
Both the answer and definition are adjectives. Perhaps you can see an association between them that I can't see?

This is all the clue.

Can you help me to learn more?

(Other definitions for sick that I've seen before include "not good" , "Ill; perverted" , "Ailing" , "Infirm" , "vomit" .)

I've seen this clue in The Irish Times.

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