I seem most agitated on occasion (9)
I believe the answer is:
sometimes
'on occasion' is the definition.
(I've seen this before)
'i seem most agitated' is the wordplay.
'agitated' is an anagram indicator.
'i'+'seem'+'most'='iseemmost'
'iseemmost' with letters rearranged gives 'SOMETIMES'.
(Other definitions for sometimes that I've seen before include "On occasion" , "Occasionally available" , "Not always" , "Seem moist (anag.)" .)