In a kettle, it can be warm, naturally (3)
I believe the answer is:
fur
'in' is the definition.
The definition and answer can be both substances as well as being singular nouns.
Perhaps you can see a link between them that I don't see?
I can't explain the remainder of the clue.
Can you help me to learn more?
(Other definitions for fur that I've seen before include "Coating formed on tongue of sick person" , "Animal-skin coat" , "Deposit inside kettles" , "Deposit lining kettles" , "Eg, chinchilla" .)