Crossword Genius

In favour of case that's challenging (11)

Ross

I believe the answer is:

provocative

'challenging' is the definition.
(thesaurus)

'in favour of case' is the wordplay.
'in favour of' becomes 'pro' (being pro a particular cause).
'case' becomes 'vocative' (the vocative case in grammar).
'pro'+'vocative'='PROVOCATIVE'

'that's' is the link.

(Other definitions for provocative that I've seen before include "Designed to cause anger or arousal" , "likely to cause annoyance" , "Deliberately annoying" , "Deliberately causing annoyance" , "Aggravating" .)

I've seen this clue in The Times.
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