Interrupt one's rest (5)
I believe the answer is:
break
This might be a double definition.
'interrupt' is the first definition.
(synonyms)
'one's rest' is the second definition.
'break' can be an answer for 'rest' (I've seen this before). I'm unsure of the 'one's' bit.
Can you help me to learn more?
(Other definitions for break that I've seen before include "Interrupt - rest period" , "Shatter; respite" , "Shatter; interval" , "Come to an end" , "Better opportunity" .)