Irritating irregular rise in volume (8)
I believe the answer is:
tiresome
'irritating' is the definition.
(I've seen this before)
'irregular rise in volume' is the wordplay.
'irregular' indicates an anagram.
'in' is an insertion indicator.
'volume' becomes 'tome' (I've seen this before).
'rise' is an anagram of 'ires'.
'ires' put within 'tome' is 'TIRESOME'.
(Other definitions for tiresome that I've seen before include "Tedious and boring" , "Boring, irksome (colloq.)" , "Trying, vexatious" , "Fatiguing, tedious" , "Is remote, being boring" .)