Irritation (4)
'irritation' is the definition.
(I know that irritation can be written as annoyance)
This is the entire clue.
(Other definitions for annoyance that I've seen before include "Irritation, vexation" , "trouble" , "Pain" , "Nuisance" , "Source of anger" .)
'irritation' is the definition.
(pique is irritation or annoyance)
This is all the clue.
(Other definitions for pique that I've seen before include "nark" , "Resentful feeling" , "Equip (anag.)" , "A feeling of hurt pride" , "Umbrage; irritation" .)
'irritation' is the definition.
(an itch irritates you)
This is all the clue.
(Other definitions for itch that I've seen before include "Irritating sensation on skin" , "A strong restless desire" , "Hunger, longing" , "Craving" , "Strong desire to do something" .)