Irritation (5)
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">irritation</span>' is the definition.<br/ ><span class="explanation-format__explanation">(synonyms)</span><br/ ><br/ >This is all the clue.<br/ ></span>
(Other definitions for annoyance that I've seen before include "Irritation, vexation" , "trouble" , "Pain" , "Nuisance" , "Source of anger" .)
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">irritation</span>' is the definition.<br/ ><span class="explanation-format__explanation">(pique is irritation or annoyance)</span><br/ ><br/ >This is the entire clue.<br/ ></span>
(Other definitions for pique that I've seen before include "nark" , "Resentful feeling" , "Equip (anag.)" , "A feeling of hurt pride" , "Umbrage; irritation" .)
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">irritation</span>' is the definition.<br/ ><span class="explanation-format__explanation">(an itch irritates you)</span><br/ ><br/ >This is all the clue.<br/ ></span>
(Other definitions for itch that I've seen before include "Irritating sensation on skin" , "A strong restless desire" , "Hunger, longing" , "Craving" , "Strong desire to do something" .)