Issue about old lady who doesn't live here now (8)
I believe the answer is:
emigrant
'who doesn't live here now' is the definition.
(someone who has left their country of origin)
'issue about old lady' is the wordplay.
'issue' becomes 'emit' (both can mean to give out or radiate).
'about' is an insertion indicator.
'old lady' becomes 'gran' (I've seen this before).
'emit' placed around 'gran' is 'EMIGRANT'.
(Other definitions for emigrant that I've seen before include "One going abroad permanently" , "I've left home for good" , "Time Gran went abroad to settle" , "One who leaves to live in another country" , "Write carelessly" .)