Issue limited by antivirus program (5)
I believe the answer is:
sprog
'issue' is the definition.
(sprogs can mean one's offspring or issue)
'limited by antivirus program' is the wordplay.
'limited by' says the answer is hidden in the clue (the clue contains or limits the answer).
'SPROG' is hidden in the letters of 'antivirus program'.
(Other definitions for sprog that I've seen before include "Child; recruit (mil. slang)" , "Baby (slang)" , "Infant" , "little one" , "Kid" .)