Mostly oblivious to ethics, turning up nose (5)
I believe the answer is:
aroma
'nose' is the definition.
(I've seen this before)
'mostly oblivious to ethics turning up' is the wordplay.
'mostly' means to remove the last letter (most but not all of the word).
'oblivious to ethics' becomes 'amoral' (having no morals).
'turning up' shows that the letters should be reversed in order.
'amoral' with its final letter removed is 'amora'.
'amora' backwards is 'AROMA'.
(Other definitions for aroma that I've seen before include "Perfume" , "Subtle quality" , "Pleasant odour" , "Savour" , "Pervasive quality" .)