Its disturbing when virtue and sin are confused (9)
I believe the answer is:
intrusive
'its disturbing' is the definition.
(to intrude on is to disturb)
'virtue and sin are confused' is the wordplay.
'and' says to put letters next to each other.
'are confused' is an anagram indicator.
'virtue' after 'sin' is 'sinvirtue'.
'sinvirtue' with letters rearranged gives 'INTRUSIVE'.
'when' acts as a link.
(Other definitions for intrusive that I've seen before include "Meddlesome" , "disturbing" , "Being present uninvited" , "Tending to enter uninvited" , "Presumptuous" .)