It's funny how, between centuries, I'm out for a duck! (5)

I believe the answer is:

comic

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'it's funny' is the definition.
(comic can mean funny or humorous)

I can't explain the rest of the clue.

(Other definitions for comic that I've seen before include "Comedian - humorous - children''s magazine" , "Amusing person" , "Funny entertainer, often stand-up" , "SECOND PART OF 16" , "Funny man, maybe stand-up" .)

I've seen this clue in the Evening Standard.

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