It's not difficult welcoming start of Coronation Street with delight (7)
I believe the answer is:
ecstasy
'delight' is the definition.
(I have seen 'Great delight ' mean 'ecstasy' so perhaps 'delight' could also mean 'ecstasy')
'it's not difficult welcoming start of coronation street' is the wordplay.
'it's not difficult' becomes 'easy' ('easy' is the opposite to 'difficult').
'welcoming' indicates putting letters inside (in sense of 'inviting in').
'start of' says to take the initial letters.
'street' becomes 'st'.
The first letter of 'coronation' is 'c'.
'c'+'st'='cst'
'easy' placed around 'cst' is 'ECSTASY'.
'with' acts as a link.
(Other definitions for ecstasy that I've seen before include "Rapture; drug" , "transports" , "Youth drug or unalloyed bliss" , "Jubilation" , "State of elated bliss" .)