It's played with a round ball (6)
I believe the answer is:
soccer
'ball' is the definition.
(soccer ball is a kind of ball)
I cannot understand how the remainder of the clue works.
Can you help me to learn more?
(Other definitions for soccer that I've seen before include "Ball game" , "popular game" , "Football for Americans?" , "... players playing this (colloquially)" , "American football?" .)