Jesus! What an infamous game show host (5,7)
I believe the answer is:
chris tarrant
'game show host' is the definition.
(Who Wants to Be a Millionaire host)
'jesus what' is the wordplay.
'jesus' becomes 'christ' ('Christ' can be a synonym of 'jesus').
'what' becomes 'arrant' (I can't justify this - if you can you should give a lot more credence to this answer).
'christ'+'arrant'='CHRIS TARRANT'
'an infamous' acts as a link.
I am not very happy about this link. Some or all of it may belong to another bit of the clue.
I've seen this clue in The Guardian.
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