Kinky bondage – it's said to be bad for setters? (7)
I believe the answer is:
dogbane
'it's said to be bad for setters?' is the definition.
(plant said to be poisonous to dogs eg setters)
'kinky bondage' is the wordplay.
'kinky' indicates anagramming the letters.
'bondage' anagrammed gives 'DOGBANE'.
(Other definitions for dogbane that I've seen before include "plant" , "noxious to those on leash?" .)